Table 1 Characteristics of patients with severe atopic dermatitis at start of treatment
From: Weight gain in patients with severe atopic dermatitis treated with dupilumab: a cohort study
| Methotrexate (n = 8) | Dupilumab (n = 12) | p value | |||
|---|---|---|---|---|---|
| Mean | 95% CI | Mean | 95% CI | ||
| Age (years) | 56.4 | 46.0–66.7 | 46.9 | 39.6–54.2 | 0.189 |
| Male sex (%) | 62.5 | 24.5–91.5 | 83.3 | 51.6–97.9 | 0.304 |
| EASI | 15.3 | 8.9–21.7 | 27.6 | 18.7–36.5 | 0.045* |
| POEM | 18.0 | 11.2–24.8 | 18.6 | 13.5–23.7 | 0.816 |
| VAS | 6.0 | 3.5–8.4 | 5.9 | 4.0–7.8 | 0.817 |
| DLQI | 17 | 12.3–21.7 | 9.4 | 4.5–14.3 | 0.025* |
| MADRS | 11.7 | 6.3–17.1 | 12.8 | 3.8–21.9 | 0.421 |
| Weight (kg) | 75.3 | 64.7–85.8 | 84.8 | 73.4–96.1 | 0.142 |
| BMI (kg/m2) | 24.7 | 19.9–36.1 | 27.3 | 24.0–28.4 | 0.123 |